GOLM1 and hepatocellular carcinoma: To test the direct effect of steady-state localization of GP73 on the invasive properties of hepatocellular carcinoma cells, we prepared HepG2 cells that expressed a non-secreted GP73 by transfecting a GP73-Δ(1–55) cDNA, which is devoid of the nucleic acids that encode for the N-terminal 1-55 amino acids needed for secretion [12, 19, 20].