INS and Insulin resistance: In addition, genotype AT was associated with increased TC levels (P = 0.049, b = 0.16(0.00, 0.32)), insulin resistance (P = 0.03, b = 0.74(0.06, 1.42)), and fasting insulin (FINS) (P = 0.02, b = 0.10 (0.01, 0.19)) compared with genotype TT, and showed a trend in increasing islet β-cell function by HOMA-B% (P = 0.09, b = 5.66(-0.86, 12.18)) (Table 1).