Many studies have characterized and used the EVC model, which matched or gathered many specific glaucoma features—not only an IOP increase with a reduction of AH outflow without affecting directly the TM, but also progressive RGCs degeneration, an AH TGF-β2 level increase, and TM cell death as observed in glaucomatous patients [3, 4]. This evidence concerns the gene TGFB2 and glaucoma.