CASP3 and tuberculosis: The present study demonstrates that GTE offered partial hepatic protection through reduction of serum ALT and AST enzyme activity and TB (Table 1), as well as restoring the antioxidant enzymes (SOD, CAT) activity and GSH concentration (Fig. 1), reduction of MDA level (Fig. 1a), minimization of DNA fragmentation percentage, DNA laddering, and downregulation of some apoptotic genes caspase-3 (Fig. 5e) and Bax protein expression (Fig. 6e).