The two index patients had a history of nodular sclerosing Hodgkin’s disease (HD) but had been in remission for 2 and 9 years, respectively, at the time of onset of anti-mGluR1-associated ACA; however, mGluR1 was not detected in a tumoral lymph node from one of those patients, and no tumour specimen was analysed in the second case, rendering it unclear whether the two conditions were pathophysiologically related [33]. Here, GRM1 is linked to neoplasm.