ALDOB and hepatocellular carcinoma: In the current study, we found that ALDOB expression was further reduced in patients with metastasis-inclined HCC (MIH), in those with primary HCC and venous metastases (e.g., portal vein tumor thrombus) or in those with confirmed extrahepatic metastases at follow-up, compared with metastasis-averse HCC (MAH) and in those with HCC without detectable metastases.