A Cox proportional hazards model showed that ALDOB expression level was an independent risk factor for RFS (hazard ratio [HR] 1.351, 95 % confidence interval [CI] 1.006–1.815, P = 0.045) and OS (hazard ratio [HR] 1.437, 95 % confidence interval[CI] 1.030-2.003, P = 0.033) of patients with HCC after curative hepatectomy (Table 1). This evidence concerns the gene ALDOB and hepatocellular carcinoma.