Upregulation of 48 proteins in samples of cancer patients was reported, that included several inflammation/acute phase-related proteins: A1AG1 (ORM1), A1AT (SERPINA1), AACT (SERPINA3), CO4B, CO9, HPT, ITIH4, LBP and SAA1, which upregulation was revealed also in our study. The gene discussed is SERPINA1; the disease is cancer.