Our finding that in sarcoidosis Tregs are hypersensitive towards CD95L-mediated apoptosis parallels earlier findings in SLE [25] and adds to our previously described similarities between sarcoidosis and systemic autoimmune disorders, which include the involvement of pathogenic IFN-γ-producing Th17 cells [26, 27]. This evidence concerns the gene FASLG and systemic lupus erythematosus.