Moreover, Weak to strong phosphorylated PTEN was observed in 57.5%, 87.5%, 82.5%, and 75.0% of chronic non-atrophic gastritis, intestinal metaplasia, dysplasia, and gastric cancer, respectively, indicating that phosphorylated PTEN was significantly increased in intestinal metaplasia, and dysplasia compared to chronic non-atrophic gastritis (ps < 0.001) (Figure 2A). The gene discussed is PTEN; the disease is gastric cancer.