For the fumarase deficiency, we identify these intervals of the fumarase flux: healthy stage [10,5.69), inflammation stage [5.69,3.69), pathological stage [3.69,0] μmol min−1 gDW−1 (we adopt the standard notation for half-closed intervals; [a, b) indicates that a is included and b is not included). Here, FH is linked to fumaric aciduria.