The HR for all-cause mortality in patients with serum GGT levels ≥ 29.5 IU/L was 2.13 (95% CI 1.45–2.93, P<0.001) using group with serum GGT levels < 29.5 IU/L as the reference category after adjustment for age, gender, diabetes mellitus, cardiovascular diseases, serum albumin levels, serum AST levels, serum ALT levels, HBs Ag and HCV Ab. The gene discussed is GPT; the disease is diabetes mellitus.