GJB7 and acute myeloid leukemia: Indeed, when Cx25 was knocked down in Jurkat and MV4-11 cells, both constructs decreased proliferation in the presence of 15 nM Ara-C (also known as arabinofuranosyl cytidine), a common chemotherapeutic agent used for the treatment of AML and non-Hodgkin lymphoma (Figure 5A).