Surprisingly, fibroblasts obtained from a benign prostatic hyperplasia (BPH) specimen in Zhao dataset (marked with an asterisk in Figure 5) were characterized by IL6 and CAF signatures, suggesting that gene expression characteristic of an activated stroma may be found even in lesions that still appear as non-malignant from a histological point of view. This evidence concerns the gene IL6 and benign prostatic hyperplasia.