POMC and Hypoglycemia: A baseline screen at the time of hypoglycaemia (glucose 1.4 mmol/l) showed an undetectable cortisol (<0.9 μg/l) with an insufficient rise in adenocorticotrophic hormone (ACTH) of 5 ng/l (range 5–50 ng/l) suggesting ACTH deficiency, free T4 of 1 ng/dl (range 0.69–1.69 ng/dl) and a thyroid stimulating hormone (TSH) of 4.5 mU/l.