We also predicted a 15-gene combination from the 176 genes, whose urinary proteins may serve as a good urinary biomarker for breast cancer against other cancers: B4GALT3, RAB31, EFNA1, NPNT, SEMA4A, H2AFZ, SMARCA4, H2AFY, NSF, HIST1H2AC, CDH1, H3F3A, CLTC, EZR and HLA-DQA2, with detailed prediction information given in S6 Table. The gene discussed is SEMA4A; the disease is breast cancer.