Similarly, a 19-gene combination, (EPR1, CREB3L1, BGN, CXCL10, UBE2S, INHBA, CEP55, BUB1, KIFC1, CDC45, SPATA17, CA12, CILP2, PTTG1, ADAMTS14, CLEC5A, FGD3, TNFRSF18, NEIL3), has been identified that could distinguish the MD group from the WD group with 94.2% classification accuracy (95.0% sensitivity and 92.2% specificity). Here, UBE2S is linked to Wilson disease.