Another study including 225 MLL-PTD AML patients examined 12 genes published as an abstract, in which the frequency of DNMT3A, FLT3-ITD, IDH1, IDH2, and RUNX1 mutations were 44.7%, 33.3%, 14.5%, 29.4%, and 25.8% [24]. The gene discussed is IDH2; the disease is acute myeloid leukemia.