PSEN2 and neoplasm: We chose to use the targeting of a murine tumor expressing MUC1 because the single Ad5 [E1-, E2b-]-MUC1 vector was more potent in some of the murine T-cell assays (Figures 2 and 3) compared to Tri-Ad5 than the CEA and brachyury vectors compared to Tri-Ad5.