The highest mutation frequencies for eQTL genes were observed in FGFR2, ITPR1, KIF13P, MAGI3, MGGT10, NOTCH2, SYNE1, and TACC2 for breast cancer, MAP3K4 for colon cancer, MYO1B and PIK3CD for liver cancer, IRX4 for pancreatic cancer, and LMTK2, PDLIM5, SP4, and SYNE1 for prostate cancer. This evidence concerns the gene SP4 and Familial prostate cancer.