PFDN5 and cancer: As shown on Figure 6A, BCAT1 knockdown resulted in upregulation of a number of gene nodes with previously suggested TSG function in EOC, including RBM3, THBS1, RUNX1T1 and WNT5A [22–25], as well as some TSGs, characterized in other cancer types (ADAMTS1, PFDN5/MM-1, MME, MPP1, TCEB2) [26–30].