With the hypothesis that the C-terminal fragment FLG2-4 is active against various soil- and waterborne bacteria, further P. aeruginosa strains, including P. aeruginosa ATCC 10145, 33348, 333358, 39324, PAO1, the Cystic Fibrosis (CF) clinical isolates CF 636, 640, 645, 646, and other Pseudomonas sp. This evidence concerns the gene SMOX and cystic fibrosis.