DNMT1 and non-small cell lung carcinoma: Recently, Zhao et al. [59] reported that β-elemene can significantly inhibit the proliferation of NSCLC cells by inhibiting extracellular signal-regulated kinases (ERK1/2) and the adenosine monophosphate-activated protein kinase α (AMPKα)-mediated transcription factor Sp1 and then by decreasing the protein expression of DNA (cytosine-5)-methyltransferase 1 (DNMT1).