SMARCB1 and neoplasm: The triple - SILAC (Stable Isotopic Labeling of Amino Acids in Cell Culture) protocol [15–18] was used to compare Smarcb1 deficient and proficient tumor cells (Cell line 365 [14] containing an empty retroviral vector as control (pMIG) or pMIG-Smarcb1 respectively) (Fig. 1a, b).