In IBD patients, increased levels of lymphatic growth factors VEGF-A, VEGF-C, and VEGF-D have been reported in serum and mucosa culture supernatants (Algaba et al., 2013; Bousvaros et al., 1999; D'Alessio et al., 2014; Duenas Pousa et al., 2007; Kanazawa et al., 2001; Pousa et al., 2008). This evidence concerns the gene VEGFC and inflammatory bowel disease.