In addition, significant TFE3 expression can ocassionally be seen in tumors that not harbor an associated gene fusion, such as granular cell tumor [24], paraganglioma [12], and adrenocortical carcinoma [12], these findings are of particular importance since all these tumors may show overlapping morphological features with ASPS. The gene discussed is TFE3; the disease is alveolar soft part sarcoma.