For icCSNB, mutations in CABP4, a neuronal calcium binding protein in the photoreceptor synaptic terminal, cause autosomal recessive disease [27], while CACNA1F, encoding the alpha 1f subunit of Cav1.4 calcium channel and localized in the photoreceptor ribbon synapse active zone [28] causes X-linked icCSNB [29,30]. This evidence concerns the gene CACNA1F and autosomal recessive disease.