MUC1 and colorectal carcinoma: As shown in Fig 2A, the pooled OR in random effect meta-analysis of the 15 studies evaluating the correlation of MUC1 expression with CRC node metastasis was 2.32with the corresponding 95% CI of 1.63–3.29 (χ2 = 75.92, P = 0.000, I2 = 81.6%).