eQTL databases were not only essential in the preparation of a carefully-selected set of functional SNPs, they also were instrumental in identifying candidate genes whose expression profiles could be more directly associated with the AIDS progression phenotypes: ENTPD4, CCT8, SLC35B4, MRPS7, MRPS10, DNAJB12, ZFP57, HCG27 and GUCA1B. Overall, we have found in the existing literature and in published datasets compelling biological grounds for the possible implication of the genes identified in this study in progression to AIDS. The gene discussed is ZFP57; the disease is AIDS.