Multiple antibodies directed against LGR5 (Sigma-Aldrich, HPA012530; Abgent, AP2745; Abcam, ab75850), CD44 (Abcam, ab41478) and EPHB2 (R&D, AF467) were tested on normal human colon and colorectal cancer tissues. The gene discussed is LGR5; the disease is colorectal cancer.