HPB242 treatment decreased phosphatidyl inositol 3-kinase and p-AKT expression levels, demonstrating that this survival pathway may also be inhibited by HPB242 [30]; In another study, Cui et al. found that MiR-125b inhibited tumor growth and promoted apoptosis of cervical cancer cells by targeting phosphoinositide 3-kinase catalytic subunit delta. The gene discussed is AKT1; the disease is neoplasm.