CSF3 and Decreased total neutrophil count: In terms of its effects on the hematopoietic system, α-tocopherol succinate has been found to reduce neutropenia, thrombocytopenia, and monocytopenia, but not to affect lymphocyte counts, in irradiated mice; it further enhances the number of colony-forming units in the spleen and the cellularity of bone marrow [70] and produces high levels of peripheral blood granulocyte-colony stimulating factor (G-CSF) and keratinocyte-derived chemokine.