In order to assess whether individuals with maximal changes in sclerostin also had maximal changes in PTH concentrations, we analysed individual changes of sclerostin concentrations before and after treatment of thyrotoxicosis (i.e., Δsclerostin) and correlated these data with individual changes of PTH levels before and after treatment of thyrotoxicosis (i.e., ΔPTH). This evidence concerns the gene SOST and thyrotoxicosis.