GLP-1 concentrations have no significant difference in PCOS and control healthy women (CT) in the early phase of OGTT and then reached significantly lower levels in PCOS than in CT at 180 min (P < 0.05) which also exhibited a significantly different time-dependent pattern in PCOS (P < 0.002 for PCOS versus time interaction) [26]. This evidence concerns the gene GLP1R and polycystic ovary syndrome.