In T2DM, an increase in the expression of proinflammatory cytokines such as TNF-α (tumor necrosis factor), IL-6 (interleukin-6), IL-1 (interleukin-1), and MCP-1 chemokine (monocyte chemotactic protein 1) has been demonstrated [24]. This evidence concerns the gene CCL2 and type 2 diabetes mellitus.