KMO and infection: A similar interaction would be predicted in schizophrenic patients who exhibit reduced kynurenine metabolism (Sathyasaikumar et al., 2011) or who possess one of the single nucleotide polymorphisms that suppress KMO activity (Holtze et al., 2012, Wonodi et al., 2011, Wonodi et al., 2014) and who also contract a significant infection.