The lead SNP at the ARL15 locus (rs4311394) was associated with lower adiponectin levels (p = 2.9 × 10−8), increased T2D risk (OR = 1.11, p = 3.2 × 10−3) and coronary heart disease (OR = 1.12, p = 8.5 × 10−6) [13]. This evidence concerns the gene ARL15 and type 2 diabetes mellitus.