Using Multi-lectin affinity chromatography (M-LAC) followed by analysis with nanoscale liquid chromatography coupled to tandem MS (nanoLC-MS/MS), Plavina et al. [51,52] used two proteomic methods to analyze plasma samples from psoriasis patients and found that plasma concentrations of both cytoskeletal and Ca2+-binding proteins, as well as their peptides, were increased in psoriasis patients. This evidence concerns the gene LCT and psoriasis.