IRF1 and diffuse large B-cell lymphoma: In DLBCL FGL2 expression correlates with multiple elements of the IFNγ-STAT1-IRF1 axis; supporting direct regulation, FGL2 expression has previously been shown to be responsive to IFNγ in T cells [70, 71], and was shown to act downstream of IRF1 in Th1-driven foetal loss [64].