To further identify the clinical role of DDR2 in HCC, we detected the correlations of the DDR2 protein expression with clinicopathological characteristics, including gender, age, HBsAg status, AFP level, tumor size, liver cirrhosis, capsule formation, Edmondson-Steiner grade, tumor number, vascular invasion and TNM stage. This evidence concerns the gene DDR2 and hepatocellular carcinoma.