Furthermore, DDR2 expression in the highly invasive HCC cell line (MHCC-97H) were evidently higher than those in the low invasive HCC cell lines including SMMC-7721, Huh-7, HepG2, Hep3B (P < 0.01, respectively, Fig. 1a-b). Here, DDR2 is linked to hepatocellular carcinoma.