Twist1 overexpression has been frequently found and documented in different types of cancer, including breast cancer [9, 10], gastric cancer [11, 12], hepatocellular carcinoma [13], NSCLC [14–17], prostate cancer [18, 19], and sarcomas [20], and it is becoming an important diagnostic and prognostic marker for cancer detection and monitoring in patients. This evidence concerns the gene TWIST1 and cancer.