To investigate the effect of CNAs on gene expression, we measured mRNA levels of multiple genes (MYC, SCRIB, PUF60, BOP1, SNTA1, E2F1, CD40, EYA2, NCOA3, FHIT, CRK, and SMAD2) at the common aberration regions in 48 tumor and matched normal tissues and analyzed the association with the CNAs. This evidence concerns the gene SMAD2 and neoplasm.