Multivariate Cox model analysis showed that SERPINE1 expression (HR 1.73, 95%CI 1.02–2.92, p = 0.042), tumor size (HR 2.18, 95%CI 1.29–3.70, p = 0.004) and node involvement (HR1.88, 95%CI 1.13–3.16, p = 0.016) were independent risk factors for progression-free survival (Table 3). Here, SERPINE1 is linked to neoplasm.