INS and obesity due to melanocortin 4 receptor deficiency: In addition, a study by Chen et al.23 showed that the Chinese Bama minipig showed metabolic syndromes, including obesity, insulin resistance, and increased levels of fasting serum glucose, insulin, serum triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) when fed a high-fat, high-sucrose diet (HFHSD) for eight months.