STAT6 and liposarcoma: So-called fat-forming SFT shows adipocytic differentiation to such an extent that well-differentiated liposarcoma may enter the differential diagnosis [132, 143, 151, 176] Although nuclear STAT6 expression has been shown to be a useful marker for the diagnosis of fat-forming SFT, particularly in CD34 negative cases [177] this has also been demonstrated in a significant proportion of dedifferentiated liposarcomas [108, 178].