Due to this biological relevance and rationale, we aimed to replicate the findings of rs9939609 from previous studies and evaluate the effect of three other SNPs, rs8050136 [25, 35], rs1121980 [39], and rs9926289 [40], in the first intron of FTO reported to be related to obesity and correlate these variants with plasma lipid profile to elucidate the effect, if any, of these SNPs on lipid parameters. Here, FTO is linked to obesity due to melanocortin 4 receptor deficiency.