A recent study has shown recurring rearrangements involving MYC and the immunoglobulin gene [55]; MYC gene rearrangements involving the κ and λ light chain genes and other non-Ig genes have also been described [23]; however, it is not sufficient to cause lymphoma, because low levels of t(8; 14)(q24; q32) have been detected in healthy individuals by using highly sensitive polymerase chain reaction [56]. This evidence concerns the gene MYC and lymphoma.