Statistical analysis showed that the HECA homo protein quantity was significantly correlated with the differentiation grade (r = -0.360, p = 0.000), serum AFP (r = -0.274, p = 0.008), cirrhosis (r = 0.243, p = 0.019) and tumor size (r = -0.224, p = 0.031). Here, AFP is linked to Cirrhosis.