These findings are consistent with our previously published data, as well as the data from Katanoska [17] and Iwata [11] that demonstrate a crucial role for TRPV2 in regulating calcium influx and the development of cardiomyopathy under baseline and pathological conditions and add to this wealth of information data regarding the channel and its important effects under physiologic stress conditions. This evidence concerns the gene TRPV2 and cardiomyopathy.