VIM and cervical carcinoma: Hsu et al. have reported that KCC3, one of the KCC isoforms (KCC1–KCC4), is significantly elevated in primary cervical carcinomas and its overexpression causes EMT, accompanied by cell morphological changes, downregulation of E-cadherin and β-catenin, upregulation of vimentin, and enhancement of cell proliferation and invasiveness in cervical cancer cells [124].