In our previous report, we demonstrated that total saponin from Korean red ginseng (TSKRG) is a beneficial traditional oriental medicine in platelet-mediated thrombotic disease via suppression of cyclooxygenase-1 (COX-1) and thromboxane A2 synthase (TXAS) to inhibit production of thromboxane A2 (TXA2) [27]. The gene discussed is PTGS1; the disease is thrombotic disease.