RRM1 and non-small cell lung carcinoma: Of note, the cisplatin sensitivity was relatively similar for the NSCLC cell lines which potentially could explain the lack of correlation between DKK1 and cisplatin response Moreover, the mRNA levels of the previously published markers of cisplatin resistance, RRM1 and ERCC1, were also analyzed in relation to cisplatin responsiveness (Fig. 4d-e).